Higher order structure of the ribosomal 5 S RNA
نویسندگان
چکیده
منابع مشابه
Secondary structure of 5 S ribosomal RNA.
A secondary structure model for 16S ribosomal RNA which is based on available chemical, enzymatic, and comparative sequence data shows good agreement between constraints dictated by the model and a wide variety of experimental observations. The four major structural domains created by the base-pairing scheme correspond closely to RNA fragments isolated after nuclease digestion in the presence o...
متن کاملEvolutionary changes in the higher order structure of the ribosomal 5S RNA
The structure of the ribosomal 5 S RNA was examined using Fe(II)-EDTA, a solvent-based reagent that cleaves the phosphodiester backbone of both double- and single-stranded RNA but is restricted by the three-dimensional structure. In the yeast 5 S RNA, cleavages were significantly restricted in six specific regions of the molecule; restrictions in only two of these regions were clearly dependent...
متن کاملStructure of the yeast ribosomal 5 S RNA-binding protein YL3.
A gene coding for the 5 S rRNA-binding protein (YL3) in yeast (Saccharomyces cerevisiae) was isolated using a polymerase chain reaction-amplified gene probe. The DNA sequence contains no introns and codes for a 297 amino acid (Mr = 33,741) protein. Although the protein is just 1 residue longer than in rat, unlike the high sequence homology in the 5 S rRNAs from the same organisms, only about 45...
متن کاملEvidence for several higher order structural elements in ribosomal RNA.
Comparative analysis of small subunit ribosomal RNA sequences suggests the existence of two new higher order interactions: (i) a double-helical structure involving positions 505-507 and 524-526 (Escherichia coli numbering) and (ii) an interaction between the region of position 130 and the helix located approximately between positions 180 and 195. In the first of these, one of the strands of the...
متن کاملPrimary and secondary structure of rat 28 S ribosomal RNA.
The primary structure of rat (Rattus norvegicus) 28 S rRNA is determined inferred from the sequence of cloned rDNA fragments. The rat 28 S rRNA contains 4802 nucleotides and has an estimated relative molecular mass (Mr, Na-salt) of 1.66 X 10(6). Several regions of high sequence homology with S. cerevisiae 25 S rRNA are present. These regions can be folded in characteristic base-paired structure...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1991
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(20)64359-9